Some drugs are administered by applying them to the skin (e.g., a nicotine skin patch to help a person stop smoking). The drug diffuses through the epidermis to blood vessels in the dermis. What kind of substances can pass easily through the skin by diffusion? What kind have difficulty? 275 words, 2 references Frostbite is the most common type of freezing injury. When skin temperature drops below 0°C (32°F), the skin freezes, and ice crystal formation damages tissues. a. Using figure 5.9, describe the mechanism that caused Billy’s ears and nose to become pale. How is this mechanism beneficial when the ambient temperature is decreasing? b. Explain what happened when Billy’s ears and nose periodically turned red. How is this beneficial when the ambient temperature is very cold?
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