In theory, randomly sampled reads should yield depth-of-coverage frequency histograms

In theory, randomly sampled reads should yield depth-of-coverage frequency histograms

Flag question: Question 3

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Question 3 1 pts

In theory, randomly sampled reads should yield depth-of-coverage frequency histograms with what type of distribution?

Group of answer choices

 

Bell shaped curve

 

Poisson

 

Gamma

 

Gaussian

 

Flag question: Question 4

Question 4 1 pts

In practice, how do depth-of-coverage frequency histograms differ from purely theoretical random sampling distributions?

Group of answer choices

 

High ends are extended (i.e. more high coverage repeats than expected)

 

Generally about the same, except for minor statistical sampling variations

 

Low end tails are extended (i.e. more low than expected)

 

Both tail ends are extended (i.e. more low and more high coverage than expected)

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