The following data was collected in a clinical trial evaluating a new compound designed to improve wound healing in trauma patients
1. The following data was collected in a clinical trial evaluating a new compound designed to improve wound healing in trauma patients. The new compound is compared against a placebo. After treatment for 5 days with the new compound or placebo the extent of wound healing is measured and the data are shown below.
Percent Wound Healing
Treatment 0-25% 26-50% 51-75% 76-100%
New Compound (n=125) 15 37 32 41
Placebo (n=125) 36 45 34 10
Is there a difference in the extent of wound healing by treatment? (Hint: Are treatment and the percent wound healing independent?) Run the appropriate test at a 5% level of significance.
5. The following data were collected in an experiment designed to investigate the impact of different positions of the mother during ultrasound on fetal heart rate. Fetal heart rate is measured by ultrasound in beats per minute. The study includes 20 women who are assigned to one position and have the fetal heart rate measured in that position. Each woman is between 28-32 weeks gestation. The data are shown below.
Back Side Sitting Standing
140 141 144 147
144 143 145 145
146 145 147 148
141 144 148 149
139 136 144 145
Mean = 142.0 Mean = 141.8 Mean = 145.6 Mean =146.8
Is there a significant difference in mean fetal heart rates by position? Run the test
at a 5% level of significance.
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