Details mainly on Toxico-kinetics and toxico-dynamics which related to “Lead” Dust And Fumes that a specific hazardous substance to consider (inorganic compounds)& needed A clear understanding of the toxico-kinetics and toxico-dynamics of the substance. You should summarise how the substance can gain entry to the body, how and where the substance is distributed, pathways for biotransformation if the substance is metabolised, sites of accumulation or storage, if appropriate, and pathways for elimination from the body. You should also briefly consider how the substance (or metabolite) interacts with cells and tissues to cause harm (mechanism of action) and summarise the resulting health effects
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